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A mild effect of the intervention was seen on fatigue while a moderate effect was observed on fatigability

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Its hormonal selectivity specifically the absence of cortisol elevation is a meaningful research advantage in these models, as elevated cortisol has well-documented catabolic effects on muscle tissue that would otherwise confound body composition outcomes

This creates two problems

For instance, for cell assays and toxicological research, changes in the amount of ROS or free energy in the cell impact on the capability of the cell to deal with induced stresses, thereby potentially leading to erroneous interpretation of results from in vitro assays