The exception: in March 2024, the FDA approved a supplemental indication for semaglutide 2.4 mg (Wegovy) to reduce the risk of cardiovascular death, nonfatal myocardial infarction, and nonfatal stroke in adults with established cardiovascular disease and either obesity or overweight (SELECT trial, Lincoff et al., New England Journal of Medicine 2023)
First, we sought to implement a pipeline to obtain cardiac morphometrical endpoints (LV mass [mm3], LV chamber volume [mm3] and local thickness [mm] (Dahl and Dahl, 2023)
As this product possesses both polyphenols and flavonols, it could be used in several new areas to identify new targets
Is allulose a GLP-1 agonist
Some non-invasive tests for liver fibrosis, including fibrosis 4 index (FIB-4 index), NAFLD fibrosis score (NFS), and aspartate aminotransferase-to-platelet ratio index (APRI), also improved (FIB-4 index from 2.99 to 1.66, NFS from 0.093 to -0.07, and APRI from 1.83 to 0.86)