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In study participants, the baseline A1c was 8.3% for both groups, and the baseline weight was 206 lbs

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The medications may interfere with the hormones associated with bone metabolism, individuals on the drugs may not be getting enough bone building nutrients due to appetite suppression, and the rapid weight loss may affect the bone homeostasis (maintenance) process

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Alcohol can impair hepatic gluconeogenesis and may mask the symptoms of hypoglycemia, making detection and treatment more challenging

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