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These may include: Nausea or vomiting Diarrhea or constipation Abdominal pain or bloating Heartburn or indigestion These effects are usually mild to moderate and often subside as the body adjusts to the medication

Exact prevalence is unclear from published trials, but post-market surveillance and patient forums suggest anxiety occurs in a subset of users

Normoglycemia restoration was more likely to be achieved in the intervention group for liraglutide, semaglutide and tirzepatide, but not orlistat, compared to placebo (Table 4)

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