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Transient cell cycle arrest and arterial differentiation of vein-derived Esm1 + cells Consistent with this and previous studies, the venous EC subclusters in our scRNA-seq analysis predominantly harbor proliferative cells in the G2/M or S phase (Fig

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However, based on the structure and triprotic nature of NAD + it was anticipated that the protonation of these moieties will influence the already pH-dependent redox potential of the system