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At the conclusion of the trial, the primary end-point (new infection, kidney dysfunction, or death between days 3 and 15 after the initiation of treatment) did not differ significantly between the groups (adjusted odds ratio: 0.98

Some real-world cohorts and long-term extension trials have reported comparable efficacy of biologic agents across BMI categories, especially when weight-based dosing regimens or dose optimization strategies were applied

Jannasch, H

Is there less of that going on today because local providers are able to provide that level of confidence in what the care is going to be

This delayed gastric emptying is therapeutically beneficial for glucose control and appetite regulation, but it means that stomach contents remain present for longer periods, potentially increasing the likelihood of reflux into the oesophagus