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Glibenclamide, metformin, and insulin for the treatment of gestational diabetes: a systematic review and meta-analysis

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Pancreatitis is an uncommon but serious adverse effect associated with GLP-1 receptor agonists (occurring in approximately 0.10.2% of patients)

Thus, reductions in energy intake with GLP-1Rbased pharmacotherapies reflect not only diminished appetite but may also involve a concomitant shift in food preference toward less energy-dense foods