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Draft proposals under NPPA may soon impose pricing ceilings

A clean Certificate of Analysis from the supplier is not the same as an independent third-party assay, and almost no buyer is in a position to audit the difference

A 2025 study directly challenged this in -cells, finding that cAMP/PKA/ERK signaling is diffusely distributed across the cell regardless of internalization kinetics, and that fast-internalizing agonists are paradoxically less efficient drivers of insulin secretion from perfused rat pancreata (Chen et al., 2025)

It is not just something extra we do after