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Research Landscape Published research involving GHK-Cu has explored its role in copper-associated signaling pathways, extracellular matrix communication, and structural protein regulation across multiple experimental models

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Healthy growing follicles exhibit resistance to granulosa cells apoptosis, whereas in early atretic follicles, apoptosis begins in the inner granulosa cells layer and progressively affects most granulosa cells, leading to follicular atresia (Tilly et al., 1991)

Bull World Health Organ 45:243253 Ethics declarations Ethical approval Not applicable

The peptide proved effective across multiple delivery routes, demonstrating therapeutic flexibility