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Enhanced Insulin Secretion: Activation of both GIP and GLP-1 receptors stimulates glucose-dependent insulin release from pancreatic -cells, improving postprandial and fasting glycemia while minimizing the risk of hypoglycemia

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Reflecting this evidence, clinical guidelines increasingly support GLP-1 receptor agonists as an appropriate first-line or add-on treatment option when obesity pharmacotherapy is indicated, in conjunction with comprehensive lifestyle interventions

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