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Though the exact mechanism of action of the two agents is unknown, synergistic interaction is thought to play a role.[11] Peels Trichloroacetic acid (TCA) is a superficial chemical exfoliating agent causing destruction of the epidermis with subsequent repair and rejuvenation

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In research settings, it is examined as an isolated pentadecapeptide with consistent physicochemical characteristics, which supports its use across biochemical, cellular, and preclinical experimental platforms

Baraka M, Alghamdi M, Alahmari A, Alghamdi A, Alfayez A

The review provides insights that contribute to future directions and drug discoveries for the treatment of RA