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YAP and TAZ exhibit considerable homology and conserved consensus sequences phosphorylated by LATS1/2 (HXRXXS) but can also vary in their gene-regulatory functions

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NNT activity contributes to 45% of the total NADPH in mitochondrial pool, indicating a significant role of NNT for NADPH pool maintenance, 111 and NADPH obtained by NNT is also used for the reductive carboxylation of -KG to isocitrate mediated by IDH2